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Pittsburg, PA – WomenEtcetera! a new online community for women over 50 began the year with a clear mission. “The interests and concerns of mature, modern women are our main focus,” explains Suzanne C
(Author: Suzanne Caplan
| Word Count: 528 | Published: Feb 1st 2008)
2: NF-kB Activation: Elucidating Upstream Events
NF-kB (Nuclear Factor-KappaB) is a heterodimeric protein composed of different combinations of members of the Rel family of transcription factors. The Rel/NF-kB family of transcription factors are involved mainly in stress-induced, immune, and inflammatory responses. For more details read out the article:
(Author: Stephen Jones
| Word Count: 321 | Published: Dec 31st 2007)
3: Data Validation through Tissue Analysis
IMGENEX History-Array tissue array slides are a simple, powerful, inexpensive, yet highly efficient method for expression analysis or localization studies of molecular targets at the DNA, RNA or protein level. For more details read out the article:
(Author: Stephen Jones
| Word Count: 369 | Published: Dec 30th 2007)
4: Are we "Livin" or just "Survivin"?
Apoptosis is regulated by death domain (DD) and/or caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. A novel CARD domain containing protein was recently identified and designated ARC for apoptosis repressor with CARD (1). For more details read out the article:
(Author: Stephen Jones
| Word Count: 389 | Published: Dec 30th 2007)
5: QuikChIP Chromatin Immunoprecipitation Kits
The principle of the ChIP assay is simple yet the process can be technically challenging. It is with these challenges in mind that IMGENEX developed the QuikChIP Kit for chromatin immunoprecipitation. Find out more information from the following article:
(Author: Stephen Jones
| Word Count: 455 | Published: Dec 30th 2007)
6: Epigenetic and Signal Transduction Reagents
IMGENEX offers over 90 Chromatin, DNA Methylation & Repair, and DNA Fragmentation-related antibodies, many of which have been cited in numerous peer-reviewed journals. Find out more details in the following article:
(Author: Stephen Jones
| Word Count: 481 | Published: Dec 30th 2007)
7: Faces of DARPP-32: Master Signaling Mediator in the Brain?
As a major target for dopamine-activated adenylyl cyclase and protein kinase A in the striatum, DARPP-32 plays a central role in regulating the efficacy of dopaminergic neurotransmission and can act either as a phosphatase or kinase inhibitor in a contextually dependent manner. For more detail read out the article:
(Author: Stephen Jones
| Word Count: 443 | Published: Dec 30th 2007)
8: New FOXP3Δ2 (Exon 2 Deleted) Specific Antibody
FOXP3 is a master regulator of immune homeostasis expressed specifically in CD4+ CD25+ T regulatory cells controlling their growth, development and function and generally accepted to be expressed in both mouse and human CD4+ CD25+ regulatory T cells. For more details read out the article:
(Author: Stephen Jones
| Word Count: 405 | Published: Dec 30th 2007)
9: Fundamental Immunology, Basic Immunology and Allergy Immunology
Immunology is a broad branch of biomedical science that covers the study of all aspects of the immune system in all organisms. The immune system is the body's defense against infectious organisms and other invaders. Through a series of steps called the immune response, the immune system attacks organisms and substances that invade our systems and cause disease. For more details read out the following article:-
(Author: Stephen Jones
| Word Count: 475 | Published: Dec 30th 2007)
10: GPCRs: Exploring New Paradigms
As one of the largest and most diverse protein families in nature, the G-protein coupled receptor (GPCR) superfamily play important roles in a variety of biological and pathological processes such as development and proliferation, neuromodulation, angiogenesis, metabolic disorders, inflammation, and viral infection.
(Author: Stephen Jones
| Word Count: 299 | Published: Dec 30th 2007)
11: Regulatory T Cells (Treg)
Early development and differentiation of nascent T cells inside the thymus is a complex and remarkable mechanism.These types of T-cells require a different strategy to tame their autoimmune potential. One of many immunotolerance mechanisms that immune system has developed to distinguish between self and non-self antigens is regulatory T cells or Tregs. For more details read out the article:
(Author: Stephen Jones
| Word Count: 595 | Published: Dec 30th 2007)
12: Improved RNA interference kits launched by Imgenex
RNA interference (RNAi) is the process of mRNA degradation that is induced by double-stranded RNA in a sequence-specific manner. RNAi has been observed in all eukaryotes, from yeast to mammals.
(Author: Stephen Jones
| Word Count: 583 | Published: Dec 30th 2007)
13: Toll-Like Receptor(TLR) : Unique Antibody from Imgenex
Toll-like Receptor(TLR) family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition. TLRs are evolutionarily conserved and their congeners have been found in insects, plants, and mammals. For more details read out the following article:
(Author: Stephen Jones
| Word Count: 451 | Published: Dec 30th 2007)
14: Transcriptional Factors And Regulators
All the cellular processes in living cells such as growth, development, morphogenesis and cellular differentiation are a product of gene expression programs involving complicated transcriptional regulation of several genes.
(Author: Stephen Jones
| Word Count: 288 | Published: Dec 30th 2007)
15: ATM (Ataxia Telangiectasia Mutated) Antibodies from Imgenex
ATM, the gene product mutated in the cancer susceptibility syndrome ataxia–telangiectasia, is related to proteins involved in DNA repair and cell-cycle control. In undamaged cells it is present as a dimer or oligomer molecule in which the kinase domain is silent because associated with the FAT region of another ATM monomer. For more information about ATM read out the given article:
(Author: Stephen Jones
| Word Count: 449 | Published: Dec 30th 2007)
16: Akt Family: Antibodies from Imgenex
Akt family of serine/threonine-directed kinases regulates a diverse array of biological processes, including cellular survival, proliferation, glucose homeostasis, and vascular tone and are important molecules in mammalian cellular signaling. For more information about Akt family read out the given article:
(Author: Stephen Jones
| Word Count: 329 | Published: Dec 30th 2007)
17: Actin Antibody Available in Imgenex now
Actin is a ubiquitous protein involved in the formation of filaments that are major components of the cytoskeleton. It is the monomeric subunit of microfilaments, one of the three major components of the cytoskeleton, and of thin filaments which are part of the contractile apparatus in muscle cells. For more details read out the article:
(Author: Stephen Jones
| Word Count: 452 | Published: Dec 30th 2007)
18: Second-Hand Asbestos Exposure
We've all, by now, heard the risks of inhaling asbestos fibers in factories, in houses, in schools, etc. What many people don't realize is that there is an equally large risk of second-hand exposure.
(Author: Joe Devine
| Word Count: 496 | Published: Dec 14th 2007)
19: Mohs technique used for skin cancer detection
Skin cancer is the most common form of skin cancer in humans. Skin cancer is also known as being the common form of cancer in America and generally develops in the epidermis which is the outermost lay
(Author: Jeff Klemin
| Word Count: 329 | Published: Nov 19th 2007)
20: Choosing Breast Reconstruction: What A Woman Should Consider
Each year over 180,000 new cases of breast cancer will be diagnosed. With that comes the emotion of confronting the disease head on, and the education of finding the best choices and resources availab
(Author: Dr Jeremy Williams
| Word Count: 632 | Published: Oct 21st 2007)
21: The Facts About Breast Cancer
The causes of breast cancer are not completely understood, although it is clear that a woman's age, gender and lifetime exposure to estrogen and her age at the time of her first childbirth can play an
(Author: Ann Knapp
| Word Count: 869 | Published: Sep 1st 2007)
22: Can Caffeine Cut Your Risk of Skin Cancer?
A recent study into the effects of caffeine seems to indicate that the risk of some skin cancers can be reduced by consuming moderate amounts of caffeine. The mechanism or trigger appears to involve s
(Author: Mitch Endick
| Word Count: 571 | Published: Aug 23rd 2007)
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